Precision Medicine and Pharmacogenetic (PGx) Testing
Just as all of our outside appearances are unique, so are our “internal mechanics”. It is the variances in these “mechanics” (genetic makeup) that is the main driver in individuals to
metabolize medications differently from one another. This is why a “one size fits all” way of prescribing medication does not work for much of the population. This is where precision medicine comes in. Precision medicine is a physician’s use of an individual’s genetic makeup to tailor medical treatments.
Precision medicine does not have to be an expensive or complicated process. NEXT Molecular Analytics understands not only the importance of providing physicians the information they need to prescribe the best medication for each individual patient, but also the importance of empowering patients to become more involved in their own healthcare and treatment. Patients are more likely to take medications as prescribed and to communicate with their physicians about side effects and issues if they understand and involved in their own treatment plan.
NEXT Molecular Analytics offers pharmacogenetic testing to patients through their physicians. This means that anyone can choose to have this testing done with an order from their physician. Remember, this is a once in lifetime test so these results will take a patient from birth through their last years in life. The results are provided to the ordering physician so that the patient’s current or future medication regiment can be appropriately monitored.
Knowing how a patient metabolizes medication can provide the road map for improved health by:
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Maximizing the effectiveness of a drug therapy;
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Avoiding harmful and unnecessary side effects;
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Improving patient compliance with drug administration;
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Assisting with the prevention of harmful, if not fatal, adverse drug reactions (ADRs); and
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Reducing costs of purchasing medication that is not taken due to inefficacy or side effects.
Learn More About
PGx Testing

NEXT Molecular PGX Testing
Our pharmacogenetic tests and panels are validated and compliant with the Clinical Laboratory Improvement Amendments (CLIA) for buccal (cheek) swab samples.
Tests include:
Single Gene Tests
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CYP2C19 testing for Plavix
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CYP2D6 for anti-depressants, others
NEXT Personal Medicine Panel
includes the following genes: ABCB1, ABCG2, ADRA2A, ANKK1/DRD2, APOE, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP3A4, CYP3A5, DBH, Factor II, Factor V, GABRP, GRIK4, HTR2A, KIF6, MTHFR, OPRM1, SLC01B1, UGT1A1, UGT2B15, VKORC1
NEXT Medication Management Panel
includes the following genes: ANKK1/DRD2, APOE, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, Factor II, Factor V, MTHFR, OPRM1, SLC01B1, VKORC1
Our test determines your genetic type by detecting changes or variants in one or more genes that can affect your response to certain medications (Table 1).


